6.0.x, 7.0.x, 7.2.0.x
Attempt to update Windows Defender manually via the control panel results in blocks.
Content cannot be downloaded or downloaded content fails to be applied.
The typical approach to updating Windows Defender is via Windows Updates. Traditionally updates and patches are managed by the system administrator thus our Trusted Updater does not include rules for a manual update.
If the system administrator wishes to allow end users to manually update Windows Defender, then approve msascui.exe by its hash.